Figure 3.
Effects of resveratrol on DM-induced oxidative stress. ((a)–(d)) Western blot analysis of p66shc, p47phox, and gp91phox levels in four groups. ((e), (f)) Observation of ROS by DHE staining in heart sections. Number of animals: 8 per group. ∗ p < 0.05 versus N group; ∗∗ p < 0.01 versus N group; # p < 0.05 versus DM group; ## p < 0.05 versus DM group. Bar = 50 μm. DHE: dihydroethidium; N: normal mice; DM: diabetic mice; DMR5: diabetic mice with 5 mg/kg/day resveratrol treatment; DMR25: diabetic mice with 25 mg/kg/day resveratrol treatment.