Clinical presentation of ARCI in families A, B, and C. (a,b) Thick, large dark-brown scales on the arm and face in 21-year-old affected individual (IV-2) in family A. (c,d) Fine white ichthyotic scales on the arm of a 14-year-old affected individual (VI-3) in family B. (e,f) Slightly thick dark-brown scales on the neck, arms, chest, and face of a 16-year-old affected individual (IV-7) in family C