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. Author manuscript; available in PMC: 2017 Oct 1.
Published in final edited form as: Expert Opin Biol Ther. 2016 Aug 8;16(10):1303–1309. doi: 10.1080/14712598.2016.1217988
Drug Name Sarilumab
Phase Pre-Registration.
Indication Adults with active moderate to severe rheumatoid
arthritis and incomplete response to methotrexate.
Pharmacology description Fully human monoclonal IgG1 antibody that binds
specifically to the interleukin-6 receptor alpha
Route of Administration Subcutaneous injection 150 or 200 mg every 2
weeks
Pivotal Trials MOBILITY39, 45