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Cumulative recoveries in the receptor fluid after a single application (100 nmol/cm2) of [14C]-BEH-TEBP to rat (●) or human (■) skin. A: Cumulative dose penetrated (%), B: Penetrance (pmol-eq/cm2). Dashed lines show the linear regression of the penetrance data. Data represents mean ± S.D.; N=4 rat; N=3 human. *: p<0.05; **: p<0.01; ****: p<0.0001.
