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. 2016 Nov 2;6:36412. doi: 10.1038/srep36412

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Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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roxP expression was analyzed using qRT-PCR during exponential and stationary phase P. acnes strain KPA171202 (a) (n = 6). Differences in expression levels of roxP between individual isolates of P. acnes (KPA171202, AD5, AD24) was analyzed at exponential growth phase, normalized against gapdh, and presented as relative roxP expression with KPA171202 set as 1 (b) (n = 6). RNA-sequencing of P. acnes revealed that roxP is strongly expressed in both exponential and stationary growth phases in different phylotypes of P. acnes (c,d), as well as transcriptional elements controlling the expression of roxP.