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. 2016 Oct 11;8(11):1325–1339. doi: 10.15252/emmm.201606330

Figure 6. Fc receptor expression on human lung epithelial cells.

Figure 6

  1. Human lung epithelial A549 cells and primary bronchial epithelial cells (hAECB) lack FcγR (CD16, CD64, and CD32) and FcαR (CD89) cell surface expression as analyzed by flow cytometry. Human THP1 cells serve as a positive control.
  2. The neonatal FcR (FcRn) is expressed in both A549 cells and human THP1 cells as determined by Western blotting. Data are representative of at least two independent experiments.
  3. Absolute bacterial counts (CFUs) in human THP1 macrophages 1 h after infection with MTB preincubated with the LAM‐reactive IgA1 (left) or IgG1 (right) antibody TB24PB037 or the respective isotype control antibody as indicated. Mean and SEM are indicated.
Data information: Data are representative of three independent experiments.