Fig 1.

Comparison of %Δ of vessel, lumen, and plaque volume among three groups

The volume of the vessel, lumen, and plaque at baseline were similar among the three groups. A small change in the vessel wall was observed after 8 months of statin therapy. Negative remodeling of the vessel was observed in the moderate and high cholesterol groups. In contrast, positive remodeling of the vessel was noted in the low cholesterol group. Lumen enlargement was detected in the moderate and high cholesterol groups, whereas lumen loss was observed in the low cholesterol group; however, these differences were not significant among the groups (p = 0.14). The coronary plaque volume increased in the low cholesterol group and decreased in the moderate and high cholesterol groups (p = 0.004).