Table 5. Multivariable predictors of coronary plaque progression.
Variable | Univariable Analysis |
Multivariable Analysis |
||||
---|---|---|---|---|---|---|
OR | 95%CI | p value | OR | 95%CI | p value | |
Low cholesterol at baseline* | 4.068 | 1.798–9.205 | 0.001 | 3.689 | 1.502–9.059 | 0.004 |
Age | 1.064 | 1.022–1.108 | 0.002 | 1.048 | 1.003–1.095 | 0.036 |
Men | 0.707 | 0.270–1.853 | 0.48 | |||
Body mass index (kg/mm2) | 0.956 | 0.853–1.072 | 0.45 | |||
Diabetes Mellitus | 1.907 | 0.909–3.999 | 0.088 | 1.973 | 0.851–4.574 | 0.11 |
Hypertension | 2.889 | 1.294–6.451 | 0.010 | 2.369 | 0.940–5.971 | 0.067 |
Allocated Pitavastatin | 0.674 | 0.325–1.400 | 0.29 | |||
Unstable angina pectoris | 0.791 | 0.356–1.757 | 0.57 | |||
Left anterior descending | 1.105 | 0.532–2.296 | 0.79 | |||
Left circumflex | 1.131 | 0.182–7.029 | 0.90 | |||
Right | 0.884 | 0.421–1.857 | 0.75 | |||
Drug-eluting stent use | 0.707 | 0.270–1.853 | 0.48 | |||
ACE-I or ARB | 2.265 | 1.077–4.765 | 0.031 | 1.248 | 0.516–3.017 | 0.62 |
β-blocker | 1.162 | 0.366–3.693 | 0.80 | |||
Calcium channel blocker | 1.810 | 0.868–3.773 | 0.11 | |||
Glucose (mg/dl) at baseline | 1.003 | 0.992–1.015 | 0.55 | |||
hs-CRP (µg/ml) at baseline | 1.003 | 9.90–1.016 | 0.62 | |||
Baseline plaque volume (mm3) | 0.999 | 0.997–1.002 | 0.646 |
non-high-density lipoprotein cholesterol ≦ 140mg/dl; ACE-I indicates, angiotensin-converting enzyme inhibitor; ARB, angiotensin receptor blocker; hs-CRP, high-sensitivity C-reactive protein