Table 2. Sex-specific, age-adjusted mean values and prevalence rates of baseline risk characteristics according to quartiles of hs-CRP levels.
Quartiles of hs-CRP levels |
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---|---|---|---|---|---|---|---|---|---|---|
Men |
Women |
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Q1 | Q2 | Q3 | Q4 | P for trend | Q1 | Q2 | Q3 | Q4 | P for trend | |
hs-CRP range (mg/L) | < 0.24 | 0.24–0.47 | 0.48–0.96 | ≥ 0.97 | < 0.17 | 0.17–0.35 | 0.36–0.77 | ≥0.78 | ||
hs-CRP (mg/L)# | 0.16 | 0.35 | 0.65 | 1.76 | 0.16 | 0.26 | 0.50 | 1.47 | ||
Number of participants | 205 | 206 | 205 | 205 | 427 | 430 | 429 | 428 | ||
Age (y) | 58.2 | 58.1 | 59.3 | 58.9 | 0.283 | 54.2 | 57.3 | 58.0 | 58.8 | < 0.001 |
Serum creatinine (mg/dL) | 0.76 | 0.75 | 0.76 | 0.75 | 0.233 | 0.58 | 0.57 | 0.57 | 0.57 | 0.604 |
eGFR (mL/min per 1.73m2) | 83.5 | 84.8 | 83.2 | 85.0 | 0.382 | 84.2 | 84.8 | 84.4 | 85.0 | 0.460 |
Body mass index (kg/m2) | 22.8 | 23.7 | 24.5 | 24.7 | < 0.001 | 21.3 | 22.8 | 24.0 | 24.4 | < 0.001 |
Current smokers (%) | 31 | 45 | 48 | 50 | 0.003 | 5 | 5 | 5 | 6 | 0.321 |
Alcohol intake (ethanol g/day) | 23.7 | 28 | 28.9 | 27.3 | 0.463 | 1.7 | 2.3 | 1.7 | 2.4 | 0.212 |
Serum albumin (g/dL) | 4.53 | 4.54 | 4.56 | 4.50 | 0.092 | 4.53 | 4.53 | 4.53 | 4.48 | < 0.001 |
Systolic blood pressure (mmHg) | 126 | 128 | 130 | 131 | 0.002 | 121 | 124 | 126 | 127 | < 0.001 |
Diastolic blood pressure (mmHg) | 80 | 81 | 81 | 82 | 0.145 | 74 | 76 | 77 | 77 | < 0.001 |
Use of antihypertensive medication (%) | 14 | 16 | 19 | 23 | 0.012 | 9 | 13 | 21 | 20 | < 0.001 |
Serum total cholesterol (mg/dL) | 202 | 208 | 209 | 207 | 0.339 | 220 | 223 | 224 | 220 | 0.521 |
High-density lipoprotein cholesterol (mg/dL) | 64 | 61 | 57 | 55 | < 0.001 | 72 | 68 | 64 | 61 | < 0.001 |
Cholesterol-lowering medication (%) | 2 | 3 | 4 | 6 | 0.008 | 8 | 9 | 13 | 10 | 0.669 |
Diabetes mellitus (%) | 7 | 8 | 9 | 10 | 0.25 | 4 | 3 | 4 | 5 | 0.040 |
Median values are shown.
Abbreviations: hs-CRP, high-sensitivity C-reactive protein; eGFR, estimated glomerular filtration rate.