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. 2016 Sep;11(9):1438–1444. doi: 10.4103/1673-5374.191217

Figure 5.

Figure 5

Effect of carnosine on PLP expression in the corpus callosum in the mouse model of SIVD.

(A) Effect of carnosine on PLP expression in the corpus callosum was evaluated by mean fluorescence intensity after right unilateral common carotid artery occlusion. The fluorescent indicator was Cy3 (red). Scale bar: 50 µm. (B) Quantitative analysis of PLP expression. There were no obvious differences in PLP fluorescence intensity among the sham, SIVD and carnosine groups. Data are expressed as the mean ± SEM. n = 8–10 mice in each group. I–V: Sham, SIVD, SIVD + carnosine 200 mg/kg, SIVD + carnosine 500 mg/kg and SIVD + carnosine 750 mg/kg groups, respectively. PLP: Proteolipide protein; SIVD: subcortical ischemic vascular dementia.