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. 2016 Nov 2;6:36033. doi: 10.1038/srep36033

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Copyright © 2016, The Author(s)

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(a) The sequence of miR-19a and miR-19b is highly conserved within vertebrate species. The seed-region is shaded in grey. (b) miR-19-Isoforms are encoded within the miR-17-92 cluster and its paralogs the miR-106a-363- and the miR-106b-25-cluster in mammals and zebrafish. (c) The zebrafish encodes for four different isoforms of miR-19, miR-19a-d. The sequence of their mature isoforms differs in maximal two nucleotides. Mature sequences are shaded in grey. Conserved sequence is indicated with stars (compared to miR-19b).