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. Author manuscript; available in PMC: 2017 Oct 1.
Published in final edited form as: Biol Blood Marrow Transplant. 2016 Aug 2;22(10):1893–1899. doi: 10.1016/j.bbmt.2016.07.007

Table 3.

Multivariate analysis of outcomes

Outcome Number Hazard ratio (95% CI) p-value

Relapse

HRM vs non-HRM 125 1.83 (1.41–2.36) <0.0001

Pre-transplant CR 109 1 <0.0001
    VGPR 208 1.2 (0.8–1.7) 0.3032
    PR 343 1.7 (1.2–2.3) 0.0014
    SD 34 2.0 (1.1–3.3) 0.0084
    Progression 21 3.2 (1.8–5.7) <0.0001

Planned post-transplant therapy 391 1 0.0002
    None 235 1.5 (1.2–1.9) 0.0002
    Missing 88 0.9 (0.6–1.3) 0.6177

Progression-free survival

HRM vs non-HRM 125 1.8 (1.4–2.4) <0.0001

Pre-transplant CR 109 1 <0.0001
    VGPR 208 1.2 (0.8–1.7) 0.3984
    PR 343 1.6 (1.1–2.2) 0.0026
    SD 34 1.8 (1.1–3.1) 0.0156
    Progression 21 3.0 (1.7–5.3) 0.0001

Planned post-transplant therapy 391 1 <0.0001
    None 235 1.6 (1.2–2.0) <0.0001
    Missing 88 0.9 (0.6–1.4) 0.6926

Overall survival

  HRM vs non-HRM 125 2.24 (1.53–3.27) <0.0001

  Black vs White 131 1.7 (1.1–2.5) 0.0061

  ISS/DSS III Yes vs No 221 1.8 (1.2–2.5) 0.0034

  Pre-transplant CR 109 1 0.0042
    VGPR 208 2.0 (1.0–3.8) 0.0244
    PR 343 2.2 (1.2–4.0) 0.0054
    SD 34 2.2 (0.8–5.4) 0.0996
    Progression 21 5.0 (2.1–11.3) 0.0001

Planned post-transplant therapy 391 1 0.0010
    None 236 1.9 (1.3–2.8) 0.0002
    Missing 88 1.3 (0.7–2.4) 0.2892