Table 3.
Outcome | Number | Hazard ratio (95% CI) | p-value |
---|---|---|---|
Relapse | |||
HRM vs non-HRM | 125 | 1.83 (1.41–2.36) | <0.0001 |
Pre-transplant CR | 109 | 1 | <0.0001 |
VGPR | 208 | 1.2 (0.8–1.7) | 0.3032 |
PR | 343 | 1.7 (1.2–2.3) | 0.0014 |
SD | 34 | 2.0 (1.1–3.3) | 0.0084 |
Progression | 21 | 3.2 (1.8–5.7) | <0.0001 |
Planned post-transplant therapy | 391 | 1 | 0.0002 |
None | 235 | 1.5 (1.2–1.9) | 0.0002 |
Missing | 88 | 0.9 (0.6–1.3) | 0.6177 |
Progression-free survival | |||
HRM vs non-HRM | 125 | 1.8 (1.4–2.4) | <0.0001 |
Pre-transplant CR | 109 | 1 | <0.0001 |
VGPR | 208 | 1.2 (0.8–1.7) | 0.3984 |
PR | 343 | 1.6 (1.1–2.2) | 0.0026 |
SD | 34 | 1.8 (1.1–3.1) | 0.0156 |
Progression | 21 | 3.0 (1.7–5.3) | 0.0001 |
Planned post-transplant therapy | 391 | 1 | <0.0001 |
None | 235 | 1.6 (1.2–2.0) | <0.0001 |
Missing | 88 | 0.9 (0.6–1.4) | 0.6926 |
Overall survival | |||
HRM vs non-HRM | 125 | 2.24 (1.53–3.27) | <0.0001 |
Black vs White | 131 | 1.7 (1.1–2.5) | 0.0061 |
ISS/DSS III Yes vs No | 221 | 1.8 (1.2–2.5) | 0.0034 |
Pre-transplant CR | 109 | 1 | 0.0042 |
VGPR | 208 | 2.0 (1.0–3.8) | 0.0244 |
PR | 343 | 2.2 (1.2–4.0) | 0.0054 |
SD | 34 | 2.2 (0.8–5.4) | 0.0996 |
Progression | 21 | 5.0 (2.1–11.3) | 0.0001 |
Planned post-transplant therapy | 391 | 1 | 0.0010 |
None | 236 | 1.9 (1.3–2.8) | 0.0002 |
Missing | 88 | 1.3 (0.7–2.4) | 0.2892 |