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. Author manuscript; available in PMC: 2017 Nov 1.
Published in final edited form as: Hepatology. 2016 Jul 25;64(5):1547–1558. doi: 10.1002/hep.28674

Figure 3.

Figure 3

Representative MRI-PDFF and MRE of a pair of 60 year old male twins concordant for both NAFLD (MRI-PDFF ≥5%) and hepatic fibrosis (MRE >3 kPa). Hepatic steatosis and fibrosis have significant shared gene effects with one another at 0.756 (95% CI: 0.716, 1), p=2.54e-5. Hepatic steatosis also has significant shared gene effects with BMI, systolic blood pressure, diastolic blood pressure, HDL cholesterol, triglycerides, glucose, HOMA-IR, insulin, and hemoglobin A1c, and hepatic fibrosis has significant shared gene effects with BMI, HDL cholesterol, triglycerides, glucose, HOMA-IR, insulin, and hemoglobin A1c.