Figure 2. Comparison of XLF parameters with UWBP for healthy mice (CN), mice with severe acute airway inflammation (SAA) and dexamethasone treated mice of the same model (SAA-DEX).

XLF shows significant differences between CN and SAA for b₁, b₃, b₅ und t_in. The treated mice (SAA-DEX) show intermediate values suggesting an inefficient treatment in terms of lung function. UWBP failed to display significant differences in all parameters between CN, SAA and SAA-DEX mice, indicating that our XLF approach - as the only other in-vivo LF method used in this study - has a higher sensitivity and specificity than in-vivo UWBP. Statistical significance difference of the results is indicated by (*p < 0.1, **p < 0.05).