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. Author manuscript; available in PMC: 2017 Oct 1.
Published in final edited form as: Reprod Toxicol. 2016 May 18;65:436–447. doi: 10.1016/j.reprotox.2016.05.007

Figure 6. Glutathione levels in hippocampus of 6 month old offspring that were Sham exposed or exposed to cigarette smoke on GD1-PD21.

Figure 6

Figure 6

Developmental CSE reduces hippocampus glutathione levels at maturity. A trend toward increased oxidized glutathione (GSSG, p=0.09) and impairment of the ratio of reduced to oxidized glutathione (GSH/GSSG; *p=0.10) in the hippocampus at maturity in offspring developmentally exposed to cigarette smoke, without an impact on the overall total glutathione pool (n=3 per group). The specific activity of glutathione-S-transferase was increased in the CSE group (*p=0.03) while a trend toward stimulation of glutathione reductase activity also was noted (*p=0.10).