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. Author manuscript; available in PMC: 2016 Nov 2.
Published in final edited form as: Pediatr Crit Care Med. 2015 Jul;16(6):598–600. doi: 10.1097/PCC.0000000000000460

Figure 1. Initial approach to the critically ill child with hyperferritinemic sepsis/MODS/MAS/HLH.

Figure 1

a) Send immunology, rheumatology, and hematology laboratory diagnostics.

b) Assess risk : Are risk factors for familial HLH present: age < 2 years, primary central nervous system presentation, consanguineous parents, or history of death of young family member with unexplained fever?