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. 2016 Sep 1;63(10):1353–1356. doi: 10.1093/cid/ciw601

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© The Author 2016. Published by Oxford University Press for the Infectious Diseases Society of America

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, contact journals.permissions@oup.com.

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Figure 1. — Chains of transmission within the new Ebola virus disease cluster (A) and maximum likelihood phylogenetic analysis of the sequences from the new EVD cluster in historical and geographical context (B). A, The chart depicts all patients involved in the cluster and the likely chains of transmission as revealed by epidemiological investigation and virus sequencing. The timeline of events is shown on top. The blue circle depicts the 3 additional Liberian cases, which originated from case 6. B, The new sequences were aligned with 1066 historical Ebola virus genome sequences and a maximum likelihood phylogenetic tree was estimated under the general time reversible + Gamma model using RAxML [4]. Only the relevant part of the tree including the new sequences is shown. Abbreviations: +, positive Ebola virus reverse-transcription polymerase chain reaction; Ct, cycle threshold; EBOV, Ebola virus; ETU, Ebola treatment unit; RT-PCR, reverse-transcription polymerase chain reaction.