Skip to main content
. 2016 Oct 27;36(5):e00398. doi: 10.1042/BSR20160344

Figure 7. Intermediate dose of candesartan increases renal activity of ACE2, but not ACE, in db/db mice.

Figure 7

Enzymatic activity of ACE (a, b) and ACE2 (c, d) in plasma and kidney cortex from db/+ and db/db mice treated with vehicle or candesartan (1, 5, 25 or 75 mg/kg/d). Results are presented as mean ± S.E.M. of 5–7 mice. *P<0.05 compared with vehicle-treated db/+; **P<0.05 db/db compared with db/+ of corresponding candesartan dose; †P<0.05 candesartan-treated db/db compared with vehicle-treated db/db.