Table 2.

Association of FOXO3A and the shared epitope with nonradiologic measures of disease outcome or activity in patients with inflammatory arthritis^a

	Shared epitope		FOXO3A (rs12212067)
	Odds ratio (95% CI)	P	Odds ratio (95% CI)	P
HAQ score	1.15 (1.06–1.25)	0.00019	0.94 (0.84–0.96)	0.11
DAS28	1.19 (1.02–1.38)	0.013	0.78 (0.66–0.93)	0.0029
SJC	1.22 (1.05–1.42)	0.0052	0.86 (0.73–1.03)	0.048
TJC	1.08 (0.80–1.45)	0.3	0.84 (0.59–1.20)	0.17
CRP	1.38 (1.09–1.72)	0.0032	0.74 (0.56–0.97)	0.016

^aFor outcome measures modeled with quantile regression, the values are the odds ratio (raised to the power of the observed coefficient), normal‐based 95% confidence interval (95% CI), and P value by 1‐tailed bootstrap method. For C‐reactive protein (CRP) modeled with zero‐inflated negative binomial regression, the results from the categorical (inflate) part of the model are reported: odds ratio (raised to the power of the observed coefficient for being non‐zero), 95% CI, and robust P value. HAQ = Health Assessment Questionnaire; DAS 28 = Disease Activity Score in 28 joints; SJC = swollen joint count; TJC = tender joint count.