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. 2016 Nov 2;11(11):e0164359. doi: 10.1371/journal.pone.0164359

Table 3. Differential expression of acid resistance genes.

Differential expression of the genes associated with acid resistance, and their categories as part of the acid resistance system 2 (AR2) (from ref. [49]), characterized to be partly RpoS-dependent (from ref. [51]), or up-regulated by acetate (from ref. [36]), as applicable. The last three columns are graphical indicators of non-differential expression (white cells), over- (black cells) and under-expression (light gray cells). S13 Table provides a Gene set analysis of these genes in pathways and with statistical significance.

Gene Name AR2 Partly RpoS-dependent Up-regulated by acetate 25 μg/mL 50 μg/mL 75 μg/mL 25 50 75
arnB -2.00 9.28 5.58
arnC -1.30 8.05 2.95
asr -1.70 9.75 1.78
cbpA 3.69 3.70 1.81
cfa x 1.87 1.79 1.65
dctR 6.78 6.29 2.36
dps x 7.23 3.60 1.66
gadA x x x 14.07 17.49 1.18
gadB x x x 12.22 25.60 1.90
gadC x x x 14.18 11.11 1.74
gadE x x 23.47 23.04 1.71
gadW x x x 8.33 5.69 2.25
gadX x x x 13.73 5.82 2.05
hdeA x x 6.24 28.09 2.66
hdeB x x 6.10 29.08 2.68
hdeD x x 3.04 14.86 2.98
hpf x -2.57 2.74 1.77
mdtE x 5.97 1.66 1.16
ompC x -1.05 2.80 1.33
osmC x -1.48 1.75 1.24
osmY x 1.93 3.23 1.53
slp x x 14.78 9.52 1.78
wrbA 24.76 7.66 1.76
yahO #N/A #N/A #N/A
ybaS 8.39 2.62 1.33
ybaT 4.80 1.54 1.44
ycaC 6.97 5.92 2.42
yccJ x 28.70 7.22 2.13
ydiZ 3.12 4.58 3.85
yeaQ x 9.95 6.26 3.80
yebV 1.96 3.71 1.75
ygfQ 1.25 1.49 1.67
yhiM 6.91 6.94 2.10
yiaG 14.22 8.45 4.36
yjfC -2.96 1.75 1.27