Table 1. Summary results of meta-analysis and indirect treatment comparison.
Variable a | Comparison Type | Group | Results [Mean difference (95%CI)] | P values |
---|---|---|---|---|
HbA1c, % | ||||
Meta-analysis | Dapagliflozin vs. Placebo | –0.82 [–0.95, –0.68] | < 0.00001 | |
Meta-analysis | Acarbose vs. Placebo | –0.47 [–0.86, –0.07] | 0.02 | |
ITC | Dapagliflozin vs. Acarbose | –0.35 [–0.767, 0.067] | 0.45572 | |
SBP, mmHg | ||||
Meta-analysis | Dapagliflozin vs. Placebo | –4.30 [–6.94, –1.67] | 0.001 | |
Meta-analysis | Acarbose vs. Placebo | –0.17 [–4.51, 4.17] | 0.94 | |
ITC | Dapagliflozin vs. Acarbose | –4.13 [–9.207, 0.947] | -- | |
Body Weight, kg | ||||
Meta-analysis | Dapagliflozin vs. Placebo | –1.91 [–2.31, –1.50] | < 0.00001 | |
Meta-analysis | Acarbose vs. Placebo | –1.41 [–2.63, –0.18] | 0.02 | |
ITC | Dapagliflozin vs. Acarbose | –0.50 [–1.79, 0.79] | 0.79383 |