Table 3. Clinical input variables.

	Dapagliflozin		Acarbose
Variable a	Mean	SE	Mean	SE
HbA1c reduction, %	–0.79	0.05	–0.44	0.22
SBP, mmHg	–3.28	0.93	0.85	2.75
Body weight change, kg	–2.05	0.15	–1.55	0.67
Probability symptomatic hypoglycaemia	0.011	0.008 b	0.010	0.005 b
Probability severe hypoglycaemia	0	0	0	0
Urinary tract infection	0.049	0.016 b	--	--
Genital infection	0.032	0.013 b	--	--
Gastrointestinal adverse effect	--	--	0.582	0.054 b
Therapy discontinuation	0.086	0.021	0.146	0.039

HbA1c, glycated hemoglobin; SE, standard error; SBP, systolic blood pressure.

^a Most variables were taken from pooled data of 4 included placebo-controlled studies [41–42,55–56]. Hypoglycaemia induced by acarbose was from a randomised trial [47].

^b Calculated as √ rate (1–rate)/numbers of subjects.