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. 2016 May 10;19(10):pyw048. doi: 10.1093/ijnp/pyw048

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Published by Oxford University Press on behalf of CINP 2016. This work is written by (a) US Government employee(s) and is in the public domain in the US.

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Figure 1. — Changes in endogenous serum insulin and C-peptide levels after i.v. infusion of exogenous ghrelin vs placebo. (A) There was a significant main effect for i.v. ghrelin administration, compared with placebo, in reducing serum insulin levels (F_1,42 = 4.15, P < .05). There was also a significant time effect (F_1,42 = 10.88, P < .001) but no significant ghrelin by time interaction for this outcome (P >.05). (B) There was a trend main effect for i.v. ghrelin administration compared with placebo in reducing serum C-peptide levels (F_1,36 = 3.34, P =.076) and a significant time effect on reduced serum insulin levels (F^1,36 = 9.23, P < .001), but no significant ghrelin by time interaction for this outcome (P >.05). All data are reported M ± SEM, P>.05, NS, not significant.