Table 2. Oocytes produced from female mice after superovulation.
| Oocyte count
|
|||
|---|---|---|---|
| Genotype | Cumulus cells | Mean ± SD | Range |
| AR+/+ | Surrounded | 20.3 ± 5.6 | 13-26 |
| Dissociated | 6.3 ± 3.4 | 3-11 | |
| Total | 26.5 ± 7.9 | 16-34 | |
| AR+/- | Surrounded | 17.5 ± 1.9 | 15-19 |
| Dissociated | 8.0 ± 3.4 | 4-12 | |
| Total | 25.5 ± 4.9 | 19-31 | |
| AR-/-* | Surrounded | 10.5 ± 5.6 | 5-18 |
| Dissociated | 5.8 ± 3.0 | 2-9 | |
| Total | 16.3 ± 8.2* | 7-27 | |
Female mice (n = 4 for each genotype) at age 25 days were subjected to superovulation treatment. Oocyte/cumulus masses were then surgically extracted from their oviducts, and oocytes surrounded with or not surrounded with cumulus cells were counted after hyaluronidase digestion for 10 min. Results are presented as mean ± SD. *, P < 0.05 vs. AR+/+, Student's unpaired t test.