Figure 4. Social impairment of Fmr1 knockout mice compared to wild-type control measured in Eco-HAB.
Fmr1 knockouts, n = 22. Wild-type controls, n = 10. (a) Odor-based social preference in the Eco-HAB system defined as the increase in proportion of time spent in the compartment with social odor during the first hour after its presentation, divided by the proportion of time spent in the compartment with non-social stimulus. Histogram (b) shows the distribution of in-cohort sociability for all pairs of knockout and control animals. Data are mean values and error bars represent SEM, *p<0.05, **p<0.01, ***p<0.001 (Mann-Whitney U-test).
DOI: http://dx.doi.org/10.7554/eLife.19532.018
Figure 4—source data 1. Eco-HAB measured social approach and in-cohort sociability of Fmr1 knockouts and wild-type controls.
The names of the Excel sheets refer to corresponding figures and contain data used for analysis of the behavioral measures obtained by the implementation of Eco-HAB.py software (see 'Materials and methods').
elife-19532-fig4-data1.xlsx (11KB, xlsx)
DOI: 10.7554/eLife.19532.019
Figure 4—source data 2. Eco-HAB measured social approach and in-cohort sociability of Fmr1 knockouts and wild-type controls.
The names of the Excel sheetsrefer to corresponding figures and contain data used for analysis of the behavioral measures obtained by the implementation of Eco-HAB.py software (see 'Materials and methods').
elife-19532-fig4-data2.xlsx (9.8KB, xlsx)
DOI: 10.7554/eLife.19532.020