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Infection rates of parental and recombinant VEE subtype IE viruses. Infection was determined by the presence of CPE in cell cultures inoculated with triturated mosquito bodies after oral exposure to virus (6.2–7.8 log10 pfu/blood meal) and incubation for 14 d. Filled bars represent WT or recombinant viruses containing the E2-218 Ser → Asn substitution.
