Table 5. Infection and dissemination/transmission rates of O. taeniorhynchus (Galveston, TX) infected orally with E2 VEEV subtype IE mutants.
| Virus strain | Blood meal titer, log10 pfu/ml | No. infected (%) | No. disseminated/no. infected (%) | No. with infected saliva/no. with disseminated infection (%) |
|---|---|---|---|---|
| IE.AA (strain 68U201) | 4.3-5.9 | 0/28 (0) | NA | NA |
| 7.3 | 2/21 (10) | 1/2 (50) | 0/1 (0) | |
| CPA201 | 4.3-5.9 | 4/31 (13) | ND | ND |
| 6.2-6.3 | 18/27 (67) | 12/18 (67) | 6/12 (50) | |
| 7.7 | 18/30 (60) | ND | ND | |
| IE.AAE2-E117K,S218N,S407R | 6.7-6.8 | 24/37 (65) | 7/7 (100) | ND |
| 7.8 | 3/6 (50) | ND | ND | |
| IE.AAE2-E117K | 7.1 | 7/29 (24) | ND | ND |
| IE.AAE2-S218N | 6.3 | 13/19 (68) | ND | ND |
| 6.9 | 11/14 (79) | 11/11 (100) | 9/11 (82) | |
| IE.AAE2-S407R | 7.0 | 5/34 (15) | ND | ND |
| IE.AAE2-E117K,S218N | 6.7 | 9/13 (69) | ND | ND |
| IE.AAE2-E117K,S407R | 7.0-7.2 | 19/54 (35) | 11/11 (100) | ND |
| IE.AAE2-S218N,S407R | 6.4-7.7 | 34/59 (58) | 18/21 (86) | ND |
NA, not applicable; ND, not assayed.