Table 2.
Bone variable | Unadjusted
|
Age-adjusted
|
||||
---|---|---|---|---|---|---|
OR (CI) per SD | OR (CI) per LSC | OR (CI) per SEE | OR (CI) per SD | OR (CI) per LSC | OR (CI) per SEE | |
BV/TV (fraction) | 1.04 (0.69, 1.58) | 1.04 (0.69, 1.58) | 1.02 (0.88, 1.18) | 0.94 (0.61, 1.46) | 0.94 (0.61, 1.45) | 0.98 (0.84, 1.14) |
Tb.Sp (mm) | 1.17 (0.75, 1.82) | 1.08 (0.87, 1.33) | 1.03 (0.95, 1.12) | 1.07 (0.67, 1.70) | 1.03 (0.82, 1.29) | 1.01 (0.93, 1.10) |
Tb.Sp MI (mm) | 1.16 (0.75, 1.80) | 1.09 (0.85, 1.40) | 1.04 (0.94, 1.14) | 1.06 (0.66, 1.68) | 1.03 (0.79, 1.35) | 1.01 (0.91, 1.12) |
Tb.Th (mm) | 0.67 (0.43, 1.05) | 0.31 (0.08, 1.16) | 0.61 (0.35, 1.07) | 0.63 (0.39, 1.03) | 0.26 (0.06, 1.08) | 0.57 (0.31, 1.03) |
Tb.Th MI (mm) | 0.70 (0.45, 1.08) | 0.34 (0.09, 1.26) | 0.64 (0.36, 1.10) | 0.66 (0.41, 1.06) | 0.29 (0.07, 1.17) | 0.59 (0.33, 1.07) |
Tb.N (no./mm) | 1.25 (0.81, 1.92) | 1.32 (0.77, 2.28) | 1.13 (0.89, 1.42) | 1.18 (0.75, 1.86) | 1.23 (0.69, 2.19) | 1.09 (0.85, 1.40) |
Note: Magnitude of fracture odds associated with each SD, LSC, or SEE increase (+) or decrease (−) in radius bone variables obtained from pMRI was determined using a binary logistic regression model. Models were examined with and without adjusting for age. CI = 95% CI (lower, upper).
Abbr: BV/TV, bone volume/total volume; CI, confidence interval; LSC, least significant change; MI, Model-Independent; OR, odds ratio; pMRI, peripheral magnetic resonance imaging; SD, standard deviation; SEE, standard error of the estimate; Tb.N, trabecular number; Tb.Sp, trabecular spacing; Tb.Th, trabecular thickness.