Year |
First Author / Last Author |
Animal |
Surgery |
Type of Imaging |
Notes |
1926 |
Wearn & German |
Cats |
Chest wall cut down to pleural layer. Second opening made through diaphragm down to pleura for illumination. |
Bright-field microscopy. |
First “window” through pleural wall. |
1939 |
Terry |
Cats |
Ribs are separated, 1 in. window implanted, air removed from thorax with vacuum. |
Binocular and skin microscope using polarized illumination. |
First implanted optical window. Used vacuum to draw tissue to window. |
1963 |
de Alva & Rainer |
Rabbits & Dogs |
One or two ribs are resected and 1 in. window inserted and sutured to chest wall. Skin was closed over window and animal allowed to heal. Before imaging, skin was dissected to expose window. |
Used high speed stroboscopic cinematography through a low mag (11X) objective. |
First survival window. |
1965 |
Wagner & Filley |
Dogs |
Right forelimb removed, one rib cut and window inserted and sutured. |
Reflection microscopy with 22X objective. |
First relatively motion free window without vacuum. |
1969 |
Wagner |
Dogs |
One Rib is resected, 3 in. window implanted. Threaded flange screws on window to form seal to chest wall. |
Brightfield microscopy with high-magnification 100X oil immersion objective. |
First window to use vacuum to stabilize tissue movement. |
1992 |
Groh & Goetz |
Rabbits |
One rib resected, 1.2 in. window implanted. Threaded flange screws on window to form seal to chest wall. Vacuum applied. |
Epifluorescent microscopy with 25X objective. |
First use of a vacuum window with epifluorescence. |
1994 |
Fingar & Wieman |
Rats |
2 ribs are resected, 1 in. window implanted and sutured to chest wall and skin. |
Epifluorescent microscopy with 40X objective. |
First survival window in rats. |
2000 |
Funakoshi & Mitsui |
Mice |
Entire chest wall removed. Vacuum suction ring attached to right lung. |
Confocal microscopy with a 20X objective. |
First use of vacuum window in mice. |
2005 |
Lamm & Glenny |
Rats |
Entire chest wall removed, 1 in. window attached to lung. |
Reflection and epifluorescent microscopy with a 20X objective. |
First use of vacuum window in rats. |
2008 |
Tabuchi & Keubler |
Mice |
3 ribs are resected, plastic film applied to opening to seal hole in chest wall. Air removed via intrapleural catheter. |
Epifluorescent microscopy with 20X objective. |
First to use plastic film to seal opening in chest wall. |