Suggestion for GLP is as follows:

-       Specific details of which model of stroke has been chosen (e.g., Longa vs. Koizumi), and the strain, age, sex, weight reported clearly.

-       Studies performed in a double-blinded fashion.

-       Power analysis reported.

-       Criteria for inclusion and exclusion in the study decided prior to the study, and reported.

-       Animals monitored daily (basic appearance, body weight and behavior) for any signs of distress, pain or sickness.

-       Reporting of animals excluded from the study.

-       Randomization of animals into groups.

-       Reporting of negative and positive results.

-       Reporting of length of surgery, anesthetic, body temperature and blood gases.

-       Reporting of environmental enrichment used, if any.