Chemotherapeutic drug/size of tumor	Intratumoral application	Intravenous application
Cisplatin dose (1 mg/ml) < 1 cm3	1 ml (1 mg)/cm3 of tumor
Cisplatin dose (1 mg/ml) > 1 cm3	0.5-1 ml (0.5-1 mg)/cm3 of tumor
Bleomycin dose (3,000 IU/ml) < 1 cm3	0.5 ml (1,500 IU)/cm3 of tumor	300 IU/kg
Bleomycin dose (3,000 IU/ml) > 1 cm3	0.5 - 1 ml (1,500-3,000 IU)/cm3 of tumor	300 IU/kg