Chemotherapeutic drug/size of tumor | Intratumoral application | Intravenous application |
Bleomycin dose (3,000 IU/ml) < 1 cm3 | 0.5 ml (1,500 IU)/cm3 of tumor | 300 IU/kg |
Bleomycin dose (3,000 IU/ml) > 1 cm3 | 0.5 - 1 ml (1,500 - 3,000 IU)/cm3 of tumor | 300 IU/kg |