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. 2004 Jul 26;5:20. doi: 10.1186/1471-2156-5-20

Table 4.

Comparison of the estimation of the linkage and gene order between three dominant markers in a full-sib family of n = 100 from the traditional and our model

MLE Traditional model Our model

graphic file with name 1471-2156-5-20-i92.gif graphic file with name 1471-2156-5-20-i93.gif graphic file with name 1471-2156-5-20-i94.gif
Data stimulated from [aaa] [ooo] × [aaa] [ooo]
Correct gene order Correct Incorrect Incorrect
Estimated best gene order (%a) 100 0 0
graphic file with name 1471-2156-5-20-i95.gif 0.2047 ± 0.0422 0.2048 ± 0.0422
graphic file with name 1471-2156-5-20-i96.gif 0.1980 ± 0.0436 0.1985 ± 0.0434
graphic file with name 1471-2156-5-20-i97.gif 0.3245 ± 0.0619 0.3235 ± 0.0618
graphic file with name 1471-2156-5-20-i98.gif 0.9860 ± 0.0105
graphic file with name 1471-2156-5-20-i99.gif 0.0060 ± 0.0071
graphic file with name 1471-2156-5-20-i100.gif 0.0080 ± 0.0079
Data simulated from [aao] [ooa] × [aao] [ooa]
Correct gene order Correct Incorrect Incorrect
Estimated best gene order (%a) 80 11 9
graphic file with name 1471-2156-5-20-i95.gif 0.1991 ± 0.0456 0.8165 ± 0.1003 0.9284 ± 0.0724 0.2104 ± 0.0447
graphic file with name 1471-2156-5-20-i96.gif 0.1697 ± 0.0907 0.8220 ± 0.0338 0.1636 ± 0.0608 0.2073 ± 0.0754
graphic file with name 1471-2156-5-20-i97.gif 0.3218 ± 0.0755 0.2703 ± 0.0586 0.7821 ± 0.0459 0.2944 ± 0.0929
graphic file with name 1471-2156-5-20-i98.gif 0.9952 ± 0.0058
graphic file with name 1471-2156-5-20-i99.gif 0.0045 ± 0.0058
graphic file with name 1471-2156-5-20-i100.gif 0.0003 ± 0.0015

aThe percents of a total of 200 simulations that have a largest likelihood for a given gene order estimated from the traditional approach. In this example used to examine the advantage of implementing gene orders, known linkage phases are assumed.