Table 2.
Parameter | NPD fed | HFD fed |
Body weight (gm) | 259.2 ± 5.3 | 315.0 ± 6.5*** |
plasma glucose (mg/dl) | 87.5 ± 2.5 | 111.0 ± 0.9*** |
Plasma triglycerides (mg/dl) | 41.3 ± 1.7 | 89.7 ± 7.2*** |
Plasma cholesterol (mg/dl) | 48.9 ± 3.7 | 87.5 ± 2.6*** |
Plasma Insulin (ng/ml) | 1.90 ± 0.15 | 3.05 ± 0.21* |
pD2 of 5-HT | 5.74 ± 0.09 | 6.00 ± 0.06 |
Emax of 5-HT | 30.0 ± 1.8 | 49.0 ± 2.0** |
pD2 of Ang II | 7.69 ± 0.08 | 7.31 ± 0.18 |
Emax of Ang II | 25.0 ± 3.4 | 34.0 ± 3.0* |
Each point is represented as mean ± SEM *p < 0.05, **p < 0.01 and ***p < 0.001 Vs NPD fed group