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. Author manuscript; available in PMC: 2017 Nov 1.
Published in final edited form as: Clin Cancer Res. 2016 Jun 8;22(21):5337–5348. doi: 10.1158/1078-0432.CCR-15-2973

Table 1. Lipid droplets in glioma patient tissues and overall survival.

Two separate areas from each patient in TMA were stained by TIP47 or Ki67 antibody and imaged by confocal or light microscopy. The number of LDs or Ki67 positive percentage was quantified by ImageJ software or Immunoratio, an online publically available application (49). Five images were taken from each tissue and averaged. Control dysplasia is a disorganized piece of brain tissue that was causing seizures, but it is neither cancerous nor precancerous. The term “dysplasia” represents something very different in neuropathology compared to elsewhere in the body.

ID# age at surgery Gender initial diagnosis LDs/cell Ki67 positive% OS (months)

6 51 F dysplasia 0.00 0.2 64.5
13 35 M dysplasia 0.00 0.3 35.2
24 41 M dysplasia 0.00 0.1 102.1
33 7 F dysplasia 0.00 0.6 50.1
42 36 M dysplasia 0.00 0.0 32.3
60 50 M dysplasia 0.00 0.5 20.2
70 34 M dysplasia 0.00 0.2 109.7
103 22 M dysplasia 0.00 0.1 31.4
107 26 M dysplasia 0.00 0.4 33.6
86 18 F PA 0.00 0.7 90.5
93 15 M PA 0.00 1.2 70.2
15 26 F A2 0.23 0.5 42.5
57 24 M A2 0.04 2.3 144.8
69 32 M A2 0.00 1.7 63.5
77 29 M A2 0.00 0.3 74.7
85 38 M A2 0.00 0.2 82.6
88 41 M A2 0.00 2.2 85.7
95 45 F A2 0.00 2.5 20.3
101 73 M A2 0.07 0.6 57.5
105 26 F A2 0.00 1.8 6.8
7 27 M A2-3 0.10 1.4 60.2
23 25 M A2-3 0.23 2.3 41.0
10 59 M AA 0.30 1.7 21.1
12 50 F AA 1.21 1.0 82.3
41 49 F AA 0.66 1.9 39.1
46 39 F AA 0.00 10.2 41.6
59 48 F AA 0.00 4.6 100.5
79 29 M AA 0.17 9.8 26.5
98 36 M AA 1.93 19.6 30.0
100 42 F AA 0.01 2.0 26.8
104 23 M AA 0.00 6.4 14.5
5 80 F GBM 4.10 18.5 15.7
9 54 M GBM 5.72 0.9 3.3
11 63 M GBM 14.41 5.7 19.3
21 62 M GBM 1.63 9.3 4.8
22 72 M GBM 16.20 11.5 8.3
25 67 M GBM 0.00 3.0 4.2
26 54 M GBM 23.37 16.9 23.7
28 46 M GBM 49.08 4.4 0.3
30 59 M GBM 11.33 9.8 14.5
34 53 M GBM 1.75 4.5 0.9
35 64 F GBM 36.19 22.1 15.6
38 50 F GBM 12.18 26.7 2.0
39 62 F GBM 3.25 6.7 29.3
43 51 F GBM 2.89 15.1 21.1
44 67 F GBM 0.39 4.8 0.5
45 56 M GBM 4.52 2.5 35.6
48 74 F GBM 5.82 6.6 15.1
49 62 M GBM giant cell 5.83 13.3 72.9
52 50 F GBM 3.21 3.9 43.7
54 42 M GBM 0.91 8.7 13.3
56 64 M GBM 16.93 6.8 6.0
58 51 M GBM 12.54 10.5 8.0
65 67 M GBM 0.16 7.1 10.9
66 77 M GBM 0.56 2.4 18.1
67 31 M GBM 2.25 13.2 71.5
68 79 M GBM 8.74 6.3 2.2
71 59 F GBM 8.31 14.8 8.2
76 62 F GBM 3.16 4.6 20.3
80 59 M GBM 24.42 10.7 9.3
81 76 F GBM 17.91 20.0 8.4
82 78 F GBM 5.84 9.2 0.9
83 76 M GBM 0.02 4.9 30.8
84 56 M GBM 1.48 6.5 7.5
87 69 M GBM 28.55 12.4 2.3
89 56 M GBM 1.22 3.3 17.8
90 72 F GBM 7.09 6.2 30.4
94 26 F GBM 13.94 4.2 5.1
96 64 F GBM 12.51 11.1 9.3
102 44 F GBM 18.04 2.2 4.0
106 70 M GBM 19.69 22.4 8.9
108 72 F GBM 0.50 2.6 26.7
109 42 M GBM 55.41 27.6 2.6
8 26 M O2 0.00 0.5 49.4
14 37 M O2 0.03 1.2 53.1
16 31 M O2 1.50 3.0 91.7
18 35 M O2 0.15 0.6 97.3
20 38 M O2 0.02 0.7 30.6
32 25 M recurrent O2 5.22 1.8 82.9
36 38 M O2 0.00 1.8 29.2
37 45 F O2-3 0.00 2.6 66.6
50 27 F O2 0.13 1.3 36.4
62 42 M O2 0.00 1.9 64.4
63 31 F O2 0.00 1.3 52.2
64 32 F O2 0.00 1.6 60.8
72 58 M O2 0.10 3.7 89.2
73 27 M O2 0.08 1.4 98.2
91 40 F O2 4.16 2.0 52.2
92 27 M O2 0.00 1.8 83.3
99 65 M O2 0.00 1.4 59.2
2 62 F AO 3.91 4.8 60.8
4 56 F AO 0.00 3.0 0.4
29 51 M AO 12.24 18.6 4.5
31 32 M AO 3.83 0.8 46.4
40 57 M AO 6.39 6.7 15.1
47 32 F AO 0.30 1.7 138.5
51 44 M AO 0.40 2.5 15.3
53 49 M AO 0.30 2.7 29.0
61 25 M progressed to AO 1.45 11.8 82.9
78 37 F recurrent AO 0.45 9.0 145.0