Table 1.
Details of gene mutations in FL cases carrying RRAGC mutations.
| FL Case# |
Disease status |
RRAGC cDNA |
RRAGC PROTEIN |
STAT6 | CREBBP | KMT2D/MLL2 | TNFRSF14 | EZH2 | MEF2B | HIST1H1 B-E | ARID1A | OCT2 | TP53 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FL065 | unknown | c.164 G>A/G | p.55 G>E/G | WT | M | M | WT | WT | WT | WT | WT | WT | M |
| FL006 | unknown | c.269 C>A/C | p.90 T>N/T | WT | M | M | WT | WT | WT | M | M | WT | WT |
| ML007 | untreated | c.278 T>C/T | p.93 L>S/L | - | - | - | - | - | - | - | - | - | - |
| L026 | untreated | c.343 T>C/T | p.115 W>R/W | M | M | M | WT | WT | WT | WT | WT | WT | WT |
| L042 | untreated | c.343 T>C/T | p.115 W>R/W | WT | M | WT | WT | WT | M | WT | WT | WT | WT |
| L066 | untreated | c.343 T>C/T | p.115 W>R/W | WT | M | M | WT | WT | WT | WT | WT | WT | WT |
| ML107 | relapsed | c.343 T>C/T | p.115 W>R/W | - | - | - | - | - | - | - | - | - | - |
| L050 | untreated | c.353 C>C/G | p.118 P>P/R | WT | M | M | WT | M | WT | WT | WT | WT | WT |
| L055 | relapsed | c.352 C>C/T | p.118 P>P/S | WT | M | M | WT | WT | M | M | WT | M | WT |
| FL007 | unknown | c.355 G>A/G | p.119 G>R/G | WT | WT | M | WT | WT | WT | M | WT | WT | WT |
| FL015 | unknown | c.355 G>A/G | p.119 G>R/G | WT | WT | WT | WT | WT | WT | WT | M | WT | M |
| ML104 | relapsed | c.535 A>A/G | p.179 K>K/E | - | - | - | - | - | - | - | - | - | - |