Table 2.
No trauma | Trauma-exposed
|
||||||||
---|---|---|---|---|---|---|---|---|---|
No symptoms | 1–3 symptoms | 4–5 symptoms | 6–7 symptoms | ||||||
| |||||||||
Cases, n (person-y) | 3,558 (243,699) | 7,741 (480,677) | 2,211 (119,662) | 1,412 (73,763) | 915 (46,575) | ||||
Hazard Ratio (95% Confidence Interval) | |||||||||
| |||||||||
P | P | P | P | ||||||
Model 1: Minimally adjusted model* |
1 (ref) | 1.04 (1.002–1.09) | .038 | 1.12 (1.06–1.18) | <.0001 | 1.17 (1.10–1.25) | <.0001 | 1.20 (1.12–1.30) | <.0001 |
Model 2: Model adjusted for biomedical covariates+ |
1 (ref) | 1.02 (0.98–1.06) | .276 | 1.09 (1.03–1.15) | .002 | 1.13 (1.06–1.20) | .0002 | 1.13 (1.05–1.21) | .001 |
Model 3: Pathways model 1† |
1 (ref) | 1.00 (0.96–1.04) | .919 | 1.07 (1.01–1.13) | .018 | 1.09 (1.03–1.16) | .006 | 1.08 (1.002–1.16) | .043 |
Model 4: Pathways model 2§ |
1 (ref) | 1.00 (0.96–1.04) | .979 | 1.06 (1.005–1.12) | .034 | 1.08 (1.01–1.15) | .020 | 1.06 (0.98–1.14) | .142 |
Adjusted for age at baseline, race/ethnicity, parental education, maternal and paternal history of hypertension, and age 5 somatotype.
Additionally adjusted for use of oral contraceptives, acetaminophen, aspirin, and other nonsteroidal anti-inflammatory drugs, menopausal status and hormone therapy use, and hypercholesterolemia.
Additionally adjusted for body mass index, physical activity, diet quality, sugar-sweetened beverage consumption, artificially-sweetened beverage consumption, cigarette smoking, and alcohol consumption.
Additionally adjusted for antidepressant use.