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. Author manuscript; available in PMC: 2017 May 1.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2016 Aug 22;25(11):1503–1510. doi: 10.1158/1055-9965.EPI-16-0147

Figure 1. Observed and predicted risks of increasing BMI on endometrial cancer.

Figure 1

The predicted effect of a 5kg/m2 increase in BMI on EC risk was estimated by scaling the effect of the per weighted allele increase in the BMIwGRS on BMI (4.83 kg/m2) by the effect of the per weighted allele increase in the BMIwGRS on EC (OR 2.11) in our dataset (exp[(4.83/5)*ln(2.11)]). The predicted effect (grey arrow) of a per 5kg/m2 increase in BMI on endometrial cancer risk (OR 2.06) is larger than that observed in our study (OR 1.55).