Table 1.
Group nomenclature.
| Strain | Age | Group nomenclature | Projections analyzed | |||||
|---|---|---|---|---|---|---|---|---|
| pNF-H | Aβ42 | ptau-231 | Total tau | SBDP | β-tubulin | |||
| D2G | 3–5 | D2G* | 8 | 12 | 4 | 4 | – | – |
| D2G | 12–15 | 8 | 6 | 4 | 4 | 4 | 4 | |
| DBA/2J | 3–5 | D3–5 | 10 | 14 | 9 | 9 | 4 | 4 |
| DBA/2J | 8–10 | D8–10 | 18 | 14 | 6 | 6 | 7** | 7** |
| DBA/2J | 12–15 | D12–15 | 16 | 18 | 6 | 6 | ||
*
Single asterisks denotes that both young and old controls were collapsed into a single group, when possible, to simplify analyses.
**
Double asterisks denotes that a new combination of ages was used for the SBDP and β-tubulin analyses. An overarching “pathological” group consisting of animals aged 10–12 months was used here.