Table 3.
Stepwise regression analyses of changes in sympathetic neural parameters following hypocaloric diet.
| Dependent variables | Step | Independent variables | Std. coeff | r2 | P |
|---|---|---|---|---|---|
| Δ Log NE (pg/ml) | 1 | Δ Insulin AUC0−120 (mU/min/L) | 0.30 | 0.09 | 0.03 |
| Δ Log NE spillover rate (ng/min) | 1 | Δ Leptin (ng/ml) | 0.33 | 0.13 | 0.01 |
| 2 | Δ PRA (ng/ml/h) | 0.29 | 0.21 | 0.03 | |
| Δ MSNA (bursts/min) | 1 | Δ BRS (msec/mmHg) | −0.31 | 0.15 | 0.046 |
| 2 | Δ LDL-C (mmol/L) | 0.30 | 0.23 | 0.049 | |
| Δ MSNA (bursts/100hb) | 1 | Δ LDL-C (mmol/L) | 0.33 | 0.11 | 0.04 |
Regression analyses were adjusted for age (years), change in body weight (kg) and change in exercise (min/day). MSNA, muscle sympathetic nerve activity; NE, norepinephrine.