Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Nov 2;3(5):ENEURO.0084-16.2016. doi: 10.1523/ENEURO.0084-16.2016

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2016 Hollis et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

PMC Copyright notice

Figure 5. — GluA1 Ser⁸⁴⁵ phosphorylation levels are reversed with administration of NBI. Animals were separated into groups (A) balanced for anxiety-like behavior on the elevated plus maze (B) and received a post-conditioning infusion of either the CRFR₁ antagonist NBI30775 or vehicle and an immediate extinction session 30 min later (C). Treatment with NBI30775 restored GluA1 Ser⁸⁴⁵ phosphorylation to vehicle home cage (HC) levels (D,E) but had no effect on GluA1 Ser⁸³¹ (D,F) or on its own (G). Data depicted as percentage of vehicle HC control group (hatched bar and also dotted line) ± SEM. *Significant difference (p < 0.05) with the vehicle-treated HC group; n = 8–12/group.