Table 1.
Baseline characteristics at time of transplantation of all patients in the study
| Total (n = 201) | ≤20 RBC units (n = 86) | >20 RBC units (n = 41) | P value* | |
|---|---|---|---|---|
| Median age (range) (n = 201) | 49 (18–70) | |||
| ≤50 years | 103 (51 %) | 43 (50 %) | 17 (41 %) | 0.37 |
| >50 years | 98 (49 %) | 43 (50 %) | 24 (59 %) | |
| Sex (male) | 119 (59 %) | 52 (61 %) | 24 (59 %) | 0.84 |
| WHO classification (n = 201) | ||||
| RA/RARS/5q- | 72 (36 %) | 26 (30 %) | 14 (34 %) | 0.90** |
| RCMD | 15 (8 %) | 3 (4 %) | 2 (5 %) | |
| RAEB-1 | 34 (17 %) | 20 (23 %) | 5 (12 %) | |
| RAEB-2 | 39 (19 %) | 18 (21 %) | 11 (27 %) | |
| MDS/AML | 41 (20 %) | 19 (22 %) | 9 (22 %) | |
| Cytogenetics (n = 152)*** | ||||
| Good | 67 (44 %) | 32 (41 %) | 17 (47 %) | 0.64 |
| Intermediate | 43 (28 %) | 24 (31 %) | 8 (22 %) | |
| Poor | 42 (28 %) | 22 (28 %) | 11 (31 %) | |
| Median time Dx-Tx | 8 (0.3–274) | |||
| ≤6 months | 80 (40 %) | 40 (47 %) | 11 (27 %) | 0.03 |
| >6 months | 121 (60 %) | 46 (53 %) | 30 (73 %) | |
| Donor type (n = 199) | ||||
| Sibling | 110 (55 %) | 42 (49 %) | 18 (45 %) | 0.65 |
| Unrelated donor | 89 (45 %) | 43 (51 %) | 22 (55 %) | |
| Match sex recipients-donor (n = 201) | ||||
| Male-female | 46 (23 %) | 19 (22 %) | 8 (20 %) | 0.74 |
| Other | 155 (77 %) | 67 (78 %) | 33 (80 %) | |
| Comorbidity (n = 145) | ||||
| No | 95 (66 %) | 54 (63 %) | 28 (68 %) | 0.54 |
| Yes | 50 (34 %) | 32 (37 %) | 13 (32 %) | |
Univariate comparisons between baseline characteristics of patients who received ≤20 RBC units and those who received >20 RBC units. (*) P values are derived from the chi-square test or Cochran-Armitage test for trend (**). According to IPSS risk categories (***)