Table 2.
Iron status parameters in control and H63D mutation group
| Variables | All (n = 83) | WT (n = 50) | H63D (n = 33) | p value |
|---|---|---|---|---|
| Fe (μg/dl) | 119.9 ± 48.8 | 99.1 ± 30.7 | 151.5 ± 54.3 | 0.0000a |
| Ferritin (ng/ml) | 32.0 ± 19.0 | 28.3 ± 15.7 | 37.6 ± 22.1 | 0.0425a |
| Ts (%) | 32.6 ± 13.7 | 27.1 ± 8.31 | 40.9 ± 16.1 | 0.0000a |
| Hb (g/dl) | 14.2 ± 1.30 | 13.8 ± 0.99 | 14.8 ± 1.47 | 0.0018a |
| RBC (ml/dl) | 4.93 ± 0.45 | 4.86 ± 0.39 | 5.02 ± 0.52 | 0.1305 |
| Ht (%) | 42.1 ± 5.70 | 40.5 ± 2.76 | 44.4 ± 7.90 | 0.0015a |
| TIBC | 224.9 ± 77.4 | 273.4 ± 45.6 | 151.5 ± 54.3 | 0.0000a |
Results are shown as means ± SD
WT wild type, Fe iron, Ts transferrin saturation, Hb hemoglobin concentration, RBC red blood cells, Ht hematocrit, TIBC total iron-binding capacity
aStatistical significant difference