Figure 4.
(a) CD68, CCR7 and CD163 macrophages gene expression studies in macrophage and fibroblast mono-cultures and fibroblast-macrophage juxtacrine (FM Juxtacrine CC) and paracrine co-culture (FM Paracrine CC) models, after 7, 14 and 21 days in TPU and ePTFE grafts. The expression levels of all marker genes were normalized to the expression levels of GAPDH. Data are expressed as mean ± SD (n = 3 per time-point per group, technical replicates: 3). (b) The ratios of CCR7/CD163 are illustrated for TPU and ePTFE grafts for macrophages mono-cultures (M) and fibroblast-macrophage juxtacrine (FM JUX) and paracrine co-culture (FM PARA) models at different time points.