Table 1.
Baseline characteristics of 114 dogs affected with degenerative mitral valvular disease according to the modified New York Heart Association (NYHA) functional classification.
| Characteristic | NYHA II (n = 38) | NYHA III (n = 46) | NYHA IV (n = 30) |
|---|---|---|---|
| Age, years | 9.5 ± 3.5 | 11.6 ± 2.7† | 12.3 ± 3.1† |
| Number of females/number of males | 24/14 | 22/24 | 15/15 |
| Body weight, kg | 5.4 ± 2.4 | 5.8 ± 3.7 | 5.3 ± 2.7 |
| Heart rate, beats per minute | 114 ± 26 | 131 ± 26† | 135 ± 27†‡ |
| Blood pressure, mmHg | 142 ± 23 | 136 ± 23 | 122 ± 19† |
| Vertebral heart scale | 9.9 ± 0.9 | 10.9 ± 0.5† | 12.5 ± 0.4†‡ |
| LA/Ao | 1.6 ± 0.3 | 1.9 ± 0.3† | 2.5 ± 0.4†‡ |
| Median survival (95% CI), months | 42 (33.7–50.3) | 26 (21.3–30.7) | 7 (3.6–10.4) |
Data are presented as mean ± SD or median (95% confidence interval [CI]).
LA/Ao, left atrium to aorta ratio.
† p < 0.05 versus class II; ‡ p < 0.05 versus class III.