Table 1. Body weight, food intake and serum parameters in PyMT and PyMT-hApoA-I mice.

	PyMT	PyMT-hApoA-I	p
Body weight (g)	22.95 ± 0.55	23.67 ± 0.58	0.38
Food intake (g/day)	3.41 ± 0.33	3.80 ± 0.16	0.29
Total serum cholesterol (mmol/L)	2.05 ± 0.10	3.72 ± 0.21	<0.0001
HDL cholesterol (mmol/L)	1.80 ± 0.14	3.56 ± 0.25	<0.0001
HDL mass (g/L)	3.08 ± 0.20	8.12 ± 0.34	<0.001
hApoA-I (g/L)	ND	2.99 ± 0.17
mApoA-I (g/L)	1.04 ± 0.10	0.66 ± 0.09	<0.05
pre-β HDL levels (% of mApoA-I)	0.51 ± 0.51	1.78 ± 0.81	0.21

Values represent the mean ± SEM for 8–10 mice/group. ND, non-detected; hApoA-I, human apoA-I; mApoA-I, mouse apoA-I. Statistical significance was considered when p ≤ 0.05 vs. the PyMT group.