Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Nov 3;6:36418. doi: 10.1038/srep36418

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

hBMSC were cultured on TCPS (CTRL) and treated with dissolved GAG derivatives as described. TNAP activity was determined from cell lysates at day 8. Diagrams show calculated values as mean ± SEM. (A) hBMSC were treated with 200 μg GAG derivative/mL for 8 days. Diagram shows TNAP activities calculated from four different donors and untreated control (CTRL) was set to 100%. Significant differences between sHA1 and CTRL, HA or Hep are indicated with c (p < 0.001) and b (p < 0.01). (B) hBMSC were treated with 200 μg HA or sHA1/mL or with the equivalent ATTO565-labeled derivative for 8 days. n = 3. (C) hBMSC were exposed to 200 μg sHA1/mL for different time frames (d1-8, d4-8, d7-8) and TNAP activities were determined at day 8. Untreated control (CTRL) was set to 100%. Significant differences between (d1-8) and CTRL, (d4-8) or (d7-8) are indicated with c (p < 0.001) and a (p < 0.05). n = 3.