Figure 4. Down-regulation of MTR significantly increased PCa cell invasion but did not alter cell proliferation in vitro.

(A) The knockdown efficiency of MTR siRNA was measured using quantitative real-time polymerase chain reaction. (B) Down-regulation of MTR did not alter LNCaP cell proliferation. (C) Down-regulation of MTR did not alter PC3 cell proliferation. (D) Down-regulation of MTR significantly increased invasion by PC3 cells. Each value represents the mean ± SD of three independent experiments, and each experiment was performed in triplicate.