Table 4. Histopathological assessment of biopsies – tubular compartment (TOV index); T – tubular necrosis, O – edema of epithelial cells, V – vacuolization of epithelial cells.
TOV* | Biopsy 1 (ST/IBT) |
Biopsy 2 (ST/IBT) |
Biopsy 3A ST |
Biopsy 3B IBT |
p 3A vs 3B | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
0 | 1 | 2 | 0 | 1 | 2 | 0 | 1 | 2 | 0 | 1 | 2 | ns | |
T | 22/22 | 1/1 | 0/0 | 9/7 | 11/9 | 5/5 | 8 | 23 | 15 | 12 | 23 | 11 | ns |
O | 17/21 | 4/2 | 1/1 | 7/11 | 10/14 | 1/3 | 13 | 26 | 7 | 16 | 25 | 5 | ns |
V | 18/16 | 3/5 | 1/3 | 7/6 | 11/12 | 6/4 | 8 | 26 | 12 | 8 | 26 | 12 | ns |
*TOV index: 0 – no changes, 1 – low grade, 2 – mild, 3 – high grade (high grade was absent in all biopsies).