TABLE 3.
Radiation Absorbed Dose for 18F-PF-05270430
| 70-kg man |
55-kg woman |
|||
| Organ | Mean (mSv/MBq) | SD (mSv/MBq) | Mean (mSv/MBq) | SD (mSv/MBq) |
| Adrenals | 1.55E–02 | 6.41E–03 | 1.84E–02 | 7.19E–03 |
| Brain | 4.76E–03 | 3.18E–03 | 6.80E–03 | 4.57E–03 |
| Breasts | 3.01E–03 | 1.43E–03 | 3.51E–03 | 1.65E–03 |
| Gallbladder wall | 1.63E–01 | 8.79E–02 | 2.01E–01 | 1.08E–01 |
| Lower large intestine wall | 6.61E–02 | 6.27E–02 | 7.01E–02 | 6.58E–02 |
| Small intestine | 7.32E–03 | 2.67E–03 | 9.04E–03 | 3.29E–03 |
| Stomach wall | 9.56E–03 | 6.66E–03 | 1.18E–02 | 7.80E–03 |
| Upper large intestine wall | 8.97E–03 | 3.42E–03 | 1.10E–02 | 4.14E–03 |
| Heart wall | 9.83E–03 | 4.17E–03 | 1.22E–02 | 5.24E–03 |
| Kidneys | 5.11E–02 | 3.20E–02 | 5.81E–02 | 3.65E–02 |
| Liver | 1.49E–01 | 8.02E–02 | 1.84E–01 | 9.91E–02 |
| Lungs | 1.13E–02 | 4.53E–03 | 1.36E–02 | 5.34E–03 |
| Muscle | 3.67E–03 | 1.38E–03 | 4.46E–03 | 1.65E–03 |
| Ovaries | 8.32E–03 | 4.51E–03 | ||
| Pancreas | 1.40E–02 | 5.95E–03 | 1.70E–02 | 7.12E–03 |
| Red marrow | 6.89E–03 | 2.44E–03 | 7.20E–03 | 2.47E–03 |
| Osteogenic cells | 4.19E–03 | 1.55E–03 | 5.48E–03 | 2.00E–03 |
| Skin | 1.87E–03 | 7.46E–04 | 2.24E–03 | 8.82E–04 |
| Spleen | 5.76E–03 | 3.62E–03 | 7.36E–03 | 4.01E–03 |
| Testes | 1.26E–03 | 6.91E–04 | ||
| Thymus | 2.61E–03 | 1.16E–03 | 3.18E–03 | 1.41E–03 |
| Thyroid | 7.12E–04 | 2.83E–04 | 8.57E–04 | 3.57E–04 |
| Urinary bladder wall | 3.22E–02 | 3.76E–02 | 4.34E–02 | 5.11E–02 |
| Uterus | 6.24E–03 | 2.83E–03 | ||
| Total body | 7.93E–03 | 3.26E–03 | 9.56E–03 | 3.85E–03 |
| Effective dose equivalent | 3.22E–02 | 1.07E–02 | 3.88E–02 | 1.29E–02 |
| Effective dose | 2.28E–02 | 8.21E–03 | 2.69E–02 | 9.28E–03 |